Statistical Methods in Translational Medicine

Antioxidants in Translational Medicine

SIGNIFICANCE It is generally accepted that reactive oxygen species (ROS) scavenging molecules or antioxidants exert health-promoting effects and thus their consumption as food additives and nutraceuticals has been greatly encouraged. Antioxidants may be beneficial in situations of subclinical deficiency and increased demand or acutely upon high-dose infusion. However, to date, there is little c...

Translational Medicine

Statistical Methods in Diagnostic Medicine using SAS Software

An important goal in diagnostic medicine research is to estimate and compare the accuracies of diagnostic tests, which serve two purposes 1) providing reliable information about a patient’s condition and 2) influencing patient care. In developing screening tools, researchers often evaluate the discriminating power of the screening test by concentrating on the sensitivity and specificity of the ...

Translational research in respiratory medicine.

S cientific research and the development of modern powerful techniques [1] are crucial for improving patient care in a society that is increasingly demanding the highest quality health services. Indeed, effective patient care requires the continuous improvement of knowledge on the pathophysiology of the diseases, diagnostic procedures and therapeutic tools available. To this end, development of...

What's next in translational medicine?

Translational medicine is the integrated application of innovative pharmacology tools, biomarkers, clinical methods, clinical technologies and study designs to improve disease understanding, confidence in human drug targets and increase confidence in drug candidates, understand the therapeutic index in humans, enhance cost-effective decision making in exploratory development and increase phase ...